Well done to all involved in this recent publication in Science outlining a thorough one step process for the purification of ethylene, the largest-volume product of the chemical industry. Full paper at: https://science.sciencemag.org/content/366/6462/241
Insights into Flow and Continuous Systems in Pharmaceutical Manufacturing: Challenges and Opportunities
Ireland’s pharmaceutical sector has transformed over the past 50 years, from an API manufacturing base to a global hub for high value activities including process R&D, formulation, bioprocessing, and biotechnology. A major recent shift has been the adoption of continuous flow technology, offering improvements in safety, efficiency, and flexibility. While integrating flow into a highly regulated environment is complex, Ireland’s ecosystem, multinational API sites, CDMOs, and innovative indigenous companies, has successfully advanced large scale API and RSM manufacture through strong collaboration with regulatory agencies. This commentary highlights key factors enabling this transition and the current state of continuous flow in API/RSM production.
https://doi.org/10.1021/acs.oprd.5c00309
Partners: Eli Lilly, MSD, Pfizer, JnJ, sk biotek, apc, almac, WAB, arran chemical, UCC, UCD, UL.
