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Crystalline Drug Substances for Improved Medicines

by tr0han | Aug 14, 2023 | Health, Impact, Small Molecule

The research Our research is aimed at the design and study of new solid-state forms of APIs. We are particularly interested in the application of sublimation as a solvent-free (i.e. green) method to control the polymorphism and crystal morphology and to obtain new...

Modelling of Multi-Phase Transport Processes to enable automation in manufacturing

by tr0han | May 25, 2023 | Biologics, Impact, Small Molecule, Sustainability

The Challenge The MOMEnTUM Spoke project is centred along diagnostic themes in specific areas of process modelling to enable control and automation within “substance” processing. The manufacture of pharmaceutics, biopharmaceutics, and chemical products is complex and...

De Souza Process – Pregabalin: Transformed Crystallization

by tr0han | May 25, 2023 | Impact, Small Molecule, Sustainability

The Challenge and background The recrystallization of Pregabalin in Isopropyl Alcohol (IPA) and Water is complex and does not follow a normal linear relationship. Pfizer circumvented this problem by elaborate azeotropic distillations to change solvent ratios post...

CM-NANO: A single process solution to formulate poorly soluble drugs as soluble nanoparticles

by tr0han | May 25, 2023 | Biologics, Impact, Small Molecule, Sustainability

CM-NANO: A single process solution to formulate poorly soluble drugs as soluble and directly compressible drug nanoparticles, is a technology to formulate poorly soluble drugs as soluble and directly compressible drug nanoparticles developed by SSPC investigator Dr...

Platform Modelling Approach to support Tablet Development, Scale-up and Technology transfer

by tr0han | Apr 27, 2023 | Impact, Small Molecule

Project Team: The collaboration includes Alkermes, Athlone, SSPC’s team at the School of Pharmacy, University College Cork, and Pharmaceutical Manufacturing Technology Centre (PMTC) at the University of Limerick. This industry-led project was devised by Stephen...
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Research & Innovation in Making Medicines. Part of the Rinn Network — Radical Collaboration.

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